Urapidil 98.0%(HPLC)

98.0%(HPLC)


Properties

Vapour pressure 0.0±1.5 mmHg at 25℃
Assay Purity >98%(HPLC)
Refractive index 1.622
B pt. 549℃ at 760 mmHg
M pt. 159℃
Density 1.26 g/cm3

Safety Information

Hazard Statement(s) H302
Precautionary Statement  P501-P270-P264-P301 + P312 + P330
Symbol
Signal word Warning
Flash point 285.8℃
Storage Temp. Store at room temperature
Storage Class 6.1
Packaging Glass Bottle
UN Number 2927

Description

Recommended products
Trans-Urocanic Acid 98.0%(HPLC)

Application
Urapidil is an 1 adrenoreceptor antagonist and a 5-HT1A receptor agonist.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Urapidil is a sympatholytic antihypertensive drug. It acts as an 1-adrenoceptor antagonist and as an 5-HT1A receptor agonist Although an initial report suggested that urapidil was also an 2-adrenoceptor agonist this was not substantiated in later studies that demonstrated it was devoid of agonist actions in the dog saphenous vein and the guinea-pig ileum. Unlike some other 1-adrenoceptor antagonists urapidil does not elicit reflex tachycardia and this may be related to its weak 1-adrenoceptor antagonist activity as well as its effect on cardiac vagal drive. Urapidil is currently not approved by the U.S. Food and Drug Administration but it is available in Europe.