Agk-2 97.0%(HPLC)

97.0%(HPLC)


Properties

Vapour pressure 0.0±2.1 mmHg at 25℃
Assay Purity >97%(HPLC)
Refractive index 1.718
B pt. 675.1±55.0 ℃ at 760 mmHg
Density 1.4±0.1 g/cm3

Safety Information

Hazard Statement(s) H302 -H312-H332-H315-H319
Precautionary Statement  P501 + P270 + P302 + P352 +P280 + P264 + P337 + P313 +P305 + P351 + P338 + P362 + P364 + P332 + P313 + P301 + P312 + P330
Symbol
Signal word Warning
Flash point 362.1±31.5℃
Storage Temp. Store at 0-10℃
Packaging Glass bottle

Description

Recommended products
2-Cyano-3-[5-(25-dichlorophenyl)furan-2-yl]-N-(quinolin-5-yl)acrylamide

Application
AGK2 is a SIRT2 inhibitor. AGK2 has been used in a study to determine that SIRT2 inhibition induces cell death and decreases the intracellular ATP level. AGK2 also rescues dopamine neurons from -synuclein toxicity in Parkinsons disease models.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
AGK 2 is a potent and selective histone deacetylase inhibitor or SIRT2 inhibitor which may be used in the treatment of parkinsons disease preventing cell death.