1H-Benzotriazol-1-Yloxytris(Dimethylamino)Phosphonium Hexafluorophosphate [Coupling Reagent For Peptide] 98.0%(HPLC)

98.0%(HPLC)


Synonym:  Castro's Reagent
Linear Formula:  C12H22F6N6OP2
Molecular Weight:  442.29g/mol
CAS Number: 56602-33-6

Properties

Assay Purity >98%(HPLC)
M pt. >130 ℃(dec.)(lit.)

Safety Information

Hazard Statement(s) H315-H319
Precautionary Statement  P264-P280-P302 + P352 -P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313
Symbol
Signal word Warning
HS Code 29339980
Flash point 138℃
Storage Temp. 2-8℃
Storage Class 4.1
Packaging Glass Bottle
UN Number 1325

Description

Application
Reagent for Peptide coupling Synthesis of esters Esterification of carboxylic acids Plasmid CAN-encapsulating liposomes Synthesis of magnolamide for antioxidative activity. Catalyst for preparation of 9-acridinecaroboxamide derivative.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
BOP reagent is a reagent commonly used in the synthesis of peptides. Its use is discouraged because coupling using BOP liberates HMPA which is carcinogenic although for small scale use in an organic laboratory this is not a great disadvantage as it is in large scale industrial usage.