Trichostatin A 98.0%(HPLC)

98.0%(HPLC)


Properties

Assay Purity >98%(HPLC)
Refractive index 1.578
M pt. 144℃(dec.)
Density 1.139 g/cm3

Safety Information

Hazard Statement(s) H302 + H312 + H332-H315-H319
Precautionary Statement  P501-P261-P270-P271-P264-P280-P337+P313-P305+P351-P338-P362+P364-P332+P313-P301+P312+P330-P302+P352+P312-P304+P340+P312
Symbol
Signal word Warning
HS Code 2924299090
Storage Temp. ?20℃
Packaging Glass Bottle

Description

Recommended products
1-Bromo-4-Propylbenzene 97.0%(GC)

Application
TSA can be used to alter gene expression by interfering with the removal of acetyl groups from histones (histone deacetylases HDAC) and therefore altering the ability of DNA transcription factors to access the DNA molecules inside chromatin.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Trichostatin A is a potent and specific inhibitor of HDAC class III with an IC50 value of 1.8 nM for HDAC.