2-Fluoro-5-Nitrobenzoic Acid 98.0%(GC)
98.0%(GC)
Synonym: 2-carboxy-4-nitrofluorobenzene
Linear Formula:
C7H4FNO4
Molecular Weight: 185.11g/mol
CAS Number: 7304-32-7
Properties
| Vapour pressure | 0.0±0.8 mmHg at 25℃ |
| Assay Purity | >98%(GC) |
| Refractive index | 1.588 |
| B pt. | 337.7℃ at 760 mmHg |
| M pt. | 139℃ |
| Density | 1.568 g/cm3 |
Safety Information
| Hazard Statement(s) | H315-H319 |
| Precautionary Statement | P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313 |
| Symbol |
|
| Signal word | Warning |
| HS Code | 2916399090 |
| Flash point | 158℃ |
| Storage Temp. | Refrigerator |
| Storage Class | 3 |
| Packaging | Glass Bottle |
| UN Number | 1993 |
Description
Recommended products
5-(2-Bromophenyl)-1H-Tetrazole 98.0%(HPLC)
Application
2-Fluoro-5-nitrobenzoic acid may be used in the synthesis of dibenz[bf]oxazepin-11(10H)-ones via the nucleophilic aromatic substitution (SNAr) of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH of various 2-aminophenols on solid support synthesis of substituted dibenzazocines on solid support via SNAr of fluorine in 2-fluoro-5-nitrobenzoic acid with the OH function of the immobilized polysubstituted phenols.
Purpose
For R&D use onlynot for drug household or other uses.
General Description
2-Fluoro-5-nitrobenzoic acid is reported to react with an aldehyde isonitrile and a primary amine tethered to a Boc-protected internal amino or hydroxyl nucleophile to afford the Ugi product.
Documents
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