6-Chloro-17-hydroxypregna-46-diene-320-dione Acetate

CMA has been used in the treatment of vaginal bleeding oligomenorrhea polymenorrhea hypermenorrhea secondary amenorrhea and endometriosis. It has also been used clinically as a hormonal contraceptive and in part due to its capacity to lower estrogen levels but also for improved effectiveness in contraception chlormadinone has frequently been combined with ethinyl estradiol for this purpose.CMA is the acetate ester of chlormadinone which in contrast to CMA was never marketed.

For R&D use onlynot for drug household or other uses.

Chlormadinone acetate (INN USAN BAN JAN) (sold under brand names including Clordion Gestafortin Lormin Non-Ovlon Normenon Verton and many others) sometimes abbreviated as CMA and also known as 17-acetoxy-6-chloro-6-dehydroprogesterone is a steroidal progestin with additional antiandrogen and antigonadotropic (and by extension antiestrogenic) effects.