E-64D [For Biochemical Research] 95.0%(HPLC)
95.0%(HPLC)
Properties
| Vapour pressure | 0.0±2.6 mmHg at 25℃ |
| Assay Purity | >95%(HPLC) |
| Refractive index | 1.53 |
| B pt. | 538℃ at 760 mmHg |
| M pt. | 126℃ |
| Density | 1.102g/cm3 |
Safety Information
| Symbol | |
| Flash point | 279.2℃ |
| Storage Temp. | '20℃ |
| Packaging | Glass Bottle |
Description
Recommended products
4-[Bis(99-Dimethylfluoren-2-Yl)Amino]Azobenzene 98.0%(HPLC)
Application
E-64d has been used as a lysosomal inhibitor in human acute promyelocytic leukemia NB4 cellsand Huh-7cells.It has also been used as a protease inhibitor in free calcium physiological tyrode solution for perfusion into the isolated heart samples.
Purpose
For R&D use onlynot for drug household or other uses.
General Description
E-64d is an inhibitor of cathepsins B and L as well as a potential inhibitor of calpain. E-64d has been shown to inhibit lysosomal proteases. E-64d has been used in combination with Prepstatin A to interfere with autolysosomal digestion. E-64d displays neurovascular and neuronal protective effects after focal cerebral ischemia in rats.
Documents
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| COA |
| Specification |
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