Lithium Bis(Trimethylsilyl)Amide


Properties

Refractive index 1.425
B pt. 114~116℃(133.322Pa)
M pt. 71-72℃
Density 0.77 g/cm3

Safety Information

Hazard Statement(s) H228 - H251 - H314
Precautionary Statement  P210 - P235 - P260 - P280 - P303 + P361 + P353 - P305 + P351 + P338
Symbol
Signal word Danger
HS Code 2931900090
Flash point '3℃
Storage Temp. Store under inert gas
Storage Class 4.1
Packaging Glass bottle
UN Number 2925

Description

Recommended products
Hexamethyldisilazane Lithium Salt (ca. 26% in Tetrahydrofuranca. 1.3molL)

Application
Base employed in generating enolates for the preparation of lactone precursorspyranonesand cyclohexanes. Used to catalyze the addition of phosphine P-H bonds to carbodiimides leading to phosphaguanidines.[1] Also used in a novel three-step synthesis of disubstituted 125-thiadiazoles.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Lithium bis(trimethylsilyl)amide is a non-nucleophilic strong Brnsted base which is generally soluble in most of the nonpolar organic solvents. It is most commonly employed in organic reactions.