1-(4-Fluorophenyl)-3-(Phenylsulfonyl)-1H-Pyrrolo[23-B]Quinoxalin-2-Amine 95.0%(HPLC)

95.0%(HPLC)


Properties

Vapour pressure 0.0±1.7 mmHg at 25℃
Assay Purity >95%(HPLC)
Refractive index 1.725
B pt. 596.2±50.0℃ at 760 mmHg
M pt. 270℃
Density 1.5±0.1 g/cm3

Safety Information

Symbol
Flash point 314.3±30.1℃
Storage Temp. Store at <0℃
Packaging Glass bottle

Description

Recommended products
1-(4-Fluorophenyl)-3-(phenylsulfonyl)-1H-pyrrolo[23-b]quinoxalin-2-amine

Purpose
For R&D use onlynot for drug household or other uses.

General Description
A cell-permeable pyrroloquinoxaline compound that acts as a reversible SIRT1 activator (10 M causes 2.3-fold fluorescent enhancement in a fluorescent assay using hrSIRT1) and enhances fat mobilization in fully differentiated 3T3L1 fibroblasts. Shown to inhibit LPS-induced TNF- release in THP-1 cells by 10-fold more potent than resveratrol (Cat.