18-Diazabicyclo (5.4.0)undec-7-ene (DBU) PurCert Standard for GC
Properties
| Vapour pressure | 5.3 mmHg ( 37.7 ℃) |
| Water Solubility | Completely miscible |
| Refractive index | n20/D 1.522-1.524 (lit.) |
| B pt. | 80-83 ℃/0.6 mmHg (lit.) |
| M pt. | -70℃ |
| Density | 1.018 g/mL at 25 ℃ (lit.) |
Safety Information
| Hazard Statement(s) | H290 - H301 - H314 - H412 |
| Precautionary Statement | P234 - P273 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Symbol |
|
| Signal word | Danger |
| HS Code | 29339930 |
| Flash point | 116℃ |
| Storage Temp. | Store at Room Temperature. |
| Storage Class | 8 |
| Packaging | Glass Bottle |
| UN Number | 3267 |
Description
Recommended products
1-[3-(Trifluoromethyl)Phenyl]Ethanol 98%
Application
18-Diazabicyclo[5.4.0]undec-7-ene (DBU) may be used as catalyst for carboxylic acid esterification with dimethyl carbonate as base for dehalogenation of halogenated Diels-Alder adducts and the resulting activated 24-dienones were subjected to regio- and stereo-directed Michael additions using Yamamotos reagent (CH3Cu BF3) in a new synthesis of the ABCD ring system of Camptothecin. 18-Diazabicyclo[5.4.0]undec-7-ene may be used as an catalyst for the dissolution and activation of cellulose by a reversible reaction of its hydroxyl groups with carbon dioxide. This dissolved cellulose system can be derivatized to form cellulose mixed esters.
Purpose
For R&D use onlynot for drug household or other uses.
General Description
18-Diazabicyclo[5.4.0]undec-7-ene is a bicyclic amidine base. It is non-nucleophilic sterically hindered tertiary amine base in organic chemistry. It is reported to be superior to amine catalyst in Baylis-Hillman reaction.It promotes the methylation reaction of phenols indoles and benzimidazoles with dimethyl carbonate under mild conditions.
Documents
| SDS | |
| COA | |
| Specification | |
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