17Alpha-Hydroxyprogesterone 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C21H30O3
Molecular Weight:  330.461 g/mol
CAS Number: 68-96-2

Properties

Vapour pressure 0.0±2.8 mmHg at 25℃
Assay Purity >98%(HPLC)
Refractive index 1.56
B pt. 482.9℃ at 760 mmHg
M pt. 220℃
Density 1.15 g/cm3

Safety Information

Hazard Statement(s) H360
Precautionary Statement  P201 - P308 + P313
Symbol
Signal word Danger
Flash point 259.9℃
Storage Temp. Store at room temperature
Storage Class 8
Packaging Poly Bottle
UN Number 3265

Description

Recommended products
17-Hydroxy-4-pregnene-320-dione

Application
17-Hydroxyprogesterone has been used for titration against ovarian S9 protein in thin-layer chromatography as a substrate for hydroxysteroid dehydrogenase from B. megaterium cultures as a cortisone analog to test its effect on voltage-dependent potassium channels (Kv1)

Purpose
For R&D use onlynot for drug household or other uses.

General Description
17-Hydroxyprogesterone (17OHP) is a cortisol precursor and is synthesized from progesterone by the action of enzyme 17-hydroxylase.[1]17OHP is a poor ligand for the nuclear progesterone receptor and an antagonist for mineralocorticoid receptor.