2-Cyanoethyl NN diisopropylchlorophosphoramidite PurReagent 95%

PurReagent


Linear Formula:  C9H18ClN2OP
Molecular Weight:  236.68 g/mol
CAS Number: 89992-70-1

Properties

Assay Purity > 95%
Refractive index n/D 1.476-1.480
B pt. 103 -105 C/0.1 hPa
Density 1.061 g/mL at 25 °C

Safety Information

Hazard Statement(s) H250,H314
Precautionary Statement  P210 - P231 + P232 - P280 - P303 + P361 + P353 - P305 + P351 + P338 - P370 + P378
Symbol
Signal word Danger
Storage Class 4.2 - Pyrophoric and self-heating hazardous materials

Description

Other Notes

This compound has the molecular formula C9H18ClN2OP a molecular weight of 236.68 gmol and CAS number 89992-70-1. Key physical properties include a density of approximately 1.06 gmL refractive index of 1.476-1.480 and boiling point around 103-105C at reduced pressure.

Purpose
The reagent activates hydroxyl groups for phosphite triester formation which oxidizes to stable phosphate linkages post-synthesis its cyanoethyl group acts as a removable protecting group under basic conditions.

General Description
2-Cyanoethyl NN-diisopropylchlorophosphoramidite is a synthetic organophosphorus reagent used in nucleic acid chemistry. It appears as a colorless to pale yellow liquid at room temperature.