3-Aminopropionitrile Fumarate 98.0%

98.0%


Linear Formula:  C7H10N2O4
Molecular Weight:  186.165 g/mol
CAS Number: 2079-89-2

Properties

Vapour pressure 5.19E-06mmHg at 25℃
Water Solubility Soluble
Assay Purity >98%
B pt. 355.5℃ at 760 mmHg
M pt. 177℃(dec.)(lit.)

Safety Information

Hazard Statement(s) H360FD
Precautionary Statement   P201 - P202 - P280 - P308 + P313 - P405 - P501P
Symbol
Signal word Danger
HS Code 2926909090
Flash point 183℃
Storage Temp. Store at 20'
Packaging Glass bottle

Description

Recommended products
B-aminopropionitrile fumarate

Application
3-Aminopropionitrile fumarate salt has been used as a lysyl oxidase (LOX) inhibitor to inhibit collagen cross-linking during microtissue formation and culture in LIM domain only 1 (LMO1)- or vector-expressing BE2C neuroblastoma cell line in transwell migration and invasion assay to study requirement of LOX activity for inducing hypoxia-inducible factor (HIF)2A-dependent stiffness in mouse organoids

General Description
In mammals metabolism of 3-aminopropionitrile leads to release of cyanide ions. Metabolic activity is localized in the microsomal fraction of the liver and is believed to proceed through a free-radical pathway.