5-Chloro-3-Methyl-1-Phenyl-1H-Pyrazole-4-Carboxaldehyde 98.0%(GC)

98.0%(GC)


Linear Formula:  C11H9ClN2O
Molecular Weight:  220.66g/mol
CAS Number: 947-95-5

Properties

Assay Purity >98%(GC)
B pt. 356.1℃ at 760 mmHg
M pt. 146℃
Density 1.26 g/cm3

Safety Information

Hazard Statement(s) H315-H319
Precautionary Statement  P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364 -P332 + P313
Symbol
Signal word Warning
HS Code 2933199090
Flash point 169.2℃
Storage Temp. Store at Room Temperature.
Packaging Glass Bottle

Description

Recommended products
9-(6-Bromohexyl)-9H-Carbazole 97.0%(GC)

Application
5-Chloro-3-methyl-1-phenyl-4-pyrazolecarboxaldehyde (5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde) may be employed as starting material for the following syntheses 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde hydrazone pyrazole derivatives which were pharmacologically evaluated for analgesic (tail flick) and anti-inflammatory (based on carrageenan-induced paw edema) activities.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
5-Chloro-3-methyl-1-phenyl-4-pyrazolecarboxaldehyde (5-Chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde) can be synthesized from 3-methyl-1-phenyl-1Hpyrazol-5(4H)-one under Vilsmeier-Haack reaction conditions.[1]Knoevenagel condensation of 5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-carboxaldehyde with ethylcyanoacetate at 0C has been reported to afford ethyl-2-cyano-3-(5-chloro-3-methyl-1-phenyl-1H-pyrazole-4-yl)propionate.