5-Ethynyl-2-Deoxyuridine 98.0%(HPLC)

98.0%(HPLC)


Synonym:  EdU
Linear Formula:  C11H12N2O5
Molecular Weight:  252.22 g/mol
CAS Number: 61135-33-9

Properties

Assay Purity >98%(HPLC)
Refractive index 1.644
M pt. 206℃
Density 1.55g/cm3

Safety Information

Hazard Statement(s) H340 - H361
Precautionary Statement  P201 - P308 + P313
Symbol
Signal word Danger
Storage Temp. ?20℃
Storage Class 3
Packaging Glass Bottle
UN Number 2049

Description

Recommended products
N-Formyl-L-Leucine

Application
5-Ethynyl-2-deoxyuridine is an extensively used nucleoside analog used as a probe for DNA synthesis. 5-Ethynyl-2-deoxyuridine is known as an toxic anti-metabolite which potentially causes DNA instabiliy necrosis and cell-cycle arrest therefore it is often used for short-term DNA synthesis in tissue culture and living organisms where prolonged cell survival is not required.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
5-Ethynyl-2-deoxyuridine (EdU) is a thymidine analog that can be incorporated into replicating DNA for detection of cell proliferation.It has an alkyne handle that can ligate with azide-containing fluorescent probes through a highly efficient click chemistry reaction.