5-Fluoroindole-23-dione

5-Fluoroisatin may be used as reaction-based probe for live-cell detection of peroxynitrite by 19F magnetic resonance spectroscopy in non-invasive detection of peroxynitrite (ONOO(-) ) formation in living lung epithelial cells stimulated with interferon- (IFN-) in the synthesis of bis-Schiff bases via condensation with aromatic primary bis-amines in water suspension medium without using any organic solvent or acid catalyst in the synthesis of 3-acetonyl-5-fluoro-3-hydroxyoxindole Reactant for preparation of Spiro[indole-thiazolidinones] as biologically relevan synthesis scaffolds Potential antimycobacterial agents Inhibitors of vitiligo disease Potential drug candidates with anti-HIV activity and anti-tubercular activity Inhibitors of TAK1 kinase Herpes simplex virus inhibitors

For R&D use onlynot for drug household or other uses.

5-Fluoroisatin has been reported as the precursor of the Sunitinib (Sutent) drug. 5-Fluoroisatin has been approved by the Food and Drugs Administration (FDA) in 2006 for the treatment of renal cell carcinoma (RCC) and gastrointestinal stromal tumor (GIST).