68-Bis(Benzylthio)Octanoic Acid 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C22H28O2S2
Molecular Weight:  388.58g/mol
CAS Number: 95809-78-2

Properties

Vapour pressure 0.0±1.6 mmHg at 25℃
Assay Purity >98%(HPLC)
Refractive index 1.595
B pt. 553.0±50.0 ℃ at 760 mmHg
M pt. 70℃
Density 1.1±0.1 g/cm3

Safety Information

Hazard Statement(s) H315-H319
Precautionary Statement  P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364 -P332 + P313
Symbol
Signal word Warning
Flash point 288.3±30.1℃
Storage Temp. 2-8℃
Storage Class 9
Packaging Glass Bottle
UN Number 3077

Description

Recommended products
26-Diisopropylphenyl Isocyanate 94%

Application
68-Bis(benzylthio)-octanoic acid has been used as pyruvate dehydrogenase (PDH) inhibitor to study its effects on neurite outgrowth in primary mouse dorsal root ganglia cells to induce -smooth muscle actin (SMA) and pro-collagen I expression and to assess PDH enzyme activity in whole-cell lysates to validate basal respiration in tissue respirometry.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
CPI 613 is a class of non-redox-active lipoate derivative that disrupts cancer cell mitochondrial metabolism and are potent anticancer agents in vivo.