Used as a certified reference standard for HPLCGC method validation impurity profiling and stability testing of beclomethasone dipropionate APIs and formulations per European Pharmacopoeia requirements.

Serves as a process-related impurity and degradation product marker to ensure pharmaceutical quality control demonstrating selective hydrolysis at the 21-position ester during storage or manufacturing.

Beclomethasone dipropionate Impurity H (EP) (CAS 5534-18-9 CHClO MW 464.98 gmol) is an off-white powder known as Beclometasone 17-propionate. It is a monoester degradation product where only the 17-position propionate ester remains on the corticosteroid backbone.