Cladribine 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C10H12ClN5O3
Molecular Weight:  285.687 g/mol
CAS Number: 4291-63-8

Properties

Vapour pressure 0.0±1.5 mmHg at 25℃
Assay Purity >98%(HPLC)
Refractive index 1.871
B pt. 547.6℃ at 760 mmHg
M pt. 220℃
Density 2.03g/cm3

Safety Information

Hazard Statement(s) H301 - H341 - H361fd - H372
Precautionary Statement  P201 - P202 - P260 - P264 - P270 - P301 + P310
Symbol
Signal word Danger
Flash point 285℃
Storage Temp. Store at <0℃
Storage Class 6.1
Packaging Glass bottle
UN Number 2811

Description

Recommended products
2-Chloro-9-(2-deoxy--D-arabinofuranosyl)adenine

Application
2-Chloro-2-deoxyadenosine (2-CdA) is a chlorinated purine nucleoside with activity against lymphoproliferative disorders such as hairy cell leukemia (HCL) and multiple myeloma (MM). 2-CdA resists ADA degradation and is phosphorylated to CdATP in lymphocytes. CdATP incorporation into DNA induces strand breaks and the activation of apoptosis. 2-CdA may also be used in studies involving the inhibition of DNA polymerase(s).

Purpose
For R&D use onlynot for drug household or other uses.