Dextran Sulfate Sodium from Dextran of Mw. Approx 40000 PurReagent

PurReagent


Linear Formula:  (C6H7Na3O14S3)n
Molecular Weight:  40000 g/mol
CAS Number: 9011-18-1

Properties

Water Solubility Completely soluble

Safety Information

Symbol
Signal word Warning
Storage Temp. Store at Room Temperature.
Storage Class 11 - Combustible Solids
Packaging Glass bottle

Description

Recommended products
1-Methylnaphthalene 96%

Application
Dextran sulfate is routinely used for the selective precipitation of lipoproteins probe hybridization membrane-immobilized DNA the release of DNA from DNA-histone complexes and the inhibition of RNA binding to ribosomes.

Purpose
Polyanionic structure disrupts colonic epithelial barrier integrity causing inflammation binds positively charged proteinslipids via electrostatic interactions stabilizes viral envelopes to enhance cell entry in pseudovirus neutralization tests.

General Description
Dextran Sulfate Sodium (DSS) from dextran (Mw 40000) is a white powder with sulfate groups that makes it highly water-soluble. Used mainly to induce colitis in animal studies stable at pH 6-8.