Glycine Ethyl Ester Monohydrochloride (H-Gly-oEt.HCl) PurCert Secondary (Working) Standard [Includes all characterization data]

PurCert


Linear Formula:  C4H9NO2.ClH
Molecular Weight:  139.58 g/mol
CAS Number: 623-33-6

Properties

Water Solubility >1000 g/L (20 ºC)
Assay Purity ? 98 %
M pt. 145-146°C(lit.)
Density 1.371 g/cm3

Safety Information

Hazard Statement(s) H318
Precautionary Statement  P280-P305+P351+P338
Symbol
Signal word Danger
HS Code 29224995
Storage Temp. 2-8°C
Storage Class 11 - Combustible Solids

Description

Application
Essential building block in solid-phase and solution-phase peptide synthesis used to prepare dipeptides glycopeptides and C-terminal ethyl ester protected peptides.

Purpose
Serves as the C-terminal component in sequential peptide coupling reactions where its amino group reacts with activated carboxylic acids of protected amino acids to form amide bonds while the ester protects the carboxyl terminus.

General Description
Glycine ethyl ester monohydrochloride (H-Gly-OEtHCl CHNOHCl MW 139.58 gmol) is the crystalline hydrochloride salt of glycine ethyl ester a white hygroscopic powder soluble in water and alcohol featuring a free -amino group and C-terminal ethyl ester protection.