Olsalazine Sodium 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C14H8N2Na2O6
Molecular Weight:  346.20 g/mol
CAS Number: 6054-98-4

Properties

Water Solubility Soluble
Assay Purity >98%(HPLC)
B pt. 557.9℃ at 760 mmHg
M pt. 294℃(dec.)

Safety Information

Hazard Statement(s) H315-H319-H335
Precautionary Statement  P264-P280-P261-P271-P302+P352-P321-P332+P313-P362+P364-P305+P351+P338-P337+P313-P304+P340-P312-P403+P233-P405-P501
Symbol
Signal word Warning
HS Code 2928000090
Flash point 291.2℃
Storage Temp. 2-8℃
Packaging Glass Bottle

Description

Recommended products
1-Chloro-4-Nitronaphthalene 98.0%(GC)

Application
Dimer of Mesalazine an anti-inflammatory drug used in the treatment of inflammatory bowel disease and ulcerative colitis.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Olsalazine is potent inhibitors of human intestinal macrophages chemotaxis to LTB4 with IC50 of 0.39 mM. Olsalazine (0.4 mM) inhibits the superoxide radical production generated by phorbol myristate acetate (PMA)-activated neutrophils or by xanthine-xanthine oxidase reaction by reduction of 31% and 73% respectively.