Oxaprozin 98.0%(HPLC)
98.0%(HPLC)
Synonym: 4,5-Diphenyl-2-oxazolepropionic Acid
Linear Formula:
C18H15NO3
Molecular Weight: 293.317 g/mol
CAS Number: 21256-18-8
Properties
| Vapour pressure | 1.6E-09mmHg at 25℃ |
| Water Solubility | Insoluble |
| Assay Purity | >98%(HPLC) |
| Refractive index | 1.595 |
| B pt. | 467℃ at 760 mmHg |
| M pt. | 163℃ |
| Density | 1.222 g/cm3 |
Safety Information
| Hazard Statement(s) | H413 |
| Precautionary Statement | P501 + P273 |
| Symbol |
|
| Signal word | Warning |
| HS Code | 2934999090 |
| Flash point | 236.2℃ |
| Storage Temp. | Store at room temperature |
| Packaging | Glass bottle |
Description
Recommended products
45-Diphenyl-2-oxazolepropionic Acid
Application
Oxaprozin is an inhibitor of both COX-1 and COX-2 with IC50s of 2.2 M and 36 M for human platelet COX-1 and IL-1-stimulated human synovial cell COX-2 respectively. Oxaprozin also inhibits the activation of NF-B.
General Description
Oxaprozin also known as Oxaprozinum (sold under the names Daypro Dayrun Duraprox) is a non-steroidal anti-inflammatory drug (NSAID) used to relieve the inflammation swelling stiffness and joint pain associated with osteoarthritis and rheumatoid arthritis. Chemically it is a propionic acid derivative. It is available in 600mg tablets. Normal adult dosage is 1200mg daily not to exceed 1800mg per day. Safety and efficacy has been established in children over 6 years with juvenile rheumatoid arthritis only and there is an increased risk of adverse reactions in the elderly population.
Documents
| SDS |
| COA |
| Specification |
| Bulk quote order form |