Propafenone Hydrochloride PurCert Secondary Reference Standard (CRM) [Includes all characterization data]

PurCert


Properties

Assay Purity > 99 %
M pt. 165-1670ƒ°C

Safety Information

Hazard Statement(s) H302
Precautionary Statement  P264 - P270 - P301 + P312 - P501
Symbol
Signal word Warning
HS Code 2922504500
Storage Temp. 2-8°C
Storage Class 11 - Combustible Solids

Description

Application
It is primarily used as an oral antiarrhythmic medication in tablet or capsule form for treating life-threatening ventricular arrhythmias and supraventricular tachycardias. It functions as a sodium channel blocker with weak beta-blocking and calcium channel blocking effects.

Purpose
Its main purpose is to stabilize cardiac cell membranes slow conduction in the His-Purkinje system and prolong PR and QRS intervals to control abnormal heart rhythms like paroxysmal supraventricular tachycardia and ventricular arrhythmias.

General Description
Propafenone Hydrochloride (CHClNO) is a white to off-white crystalline powder the hydrochloride salt of propafenone with a molecular weight of 377.9 gmol. It melts at 171-175C is slightly soluble in water soluble in methanol and exhibits maximum absorption at 303 nm.