Ribonuclease A


Synonym:  RNase A
Linear Formula:  C9H14N4O3
Molecular Weight:  226.23g/mol
CAS Number: 9001-99-4

Properties

Vapour pressure 0.0±2.1 mmHg at 25℃
Refractive index 1.591
B pt. 656.2±55.0 ℃ at 760 mmHg
M pt. 243℃(dec.)
Density 1.4±0.1 g/cm3

Safety Information

Hazard Statement(s) H319
Precautionary Statement  P305 + P351 + P338
Symbol
Signal word Warning
Flash point 350.7±31.5℃
Storage Temp. ?20℃
Packaging Glass Bottle

Description

Recommended products
Perfluoro(Tetradecahydrophenanthrene) Mixture Of Isomers

Application
RNase A is used to remove RNA from DNA plasmid and genomic DNA preparations and protein samples. RNase A is also used in RNA sequence analysis and protection assays. RNase A has been used as a tool for computer-aided drug design. RNase A supports the analysis of RNA sequences.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
RNase A Ribonuclease A is an endoribonuclease that cleaves the phosphodiester bonds of single strand RNA after pyrimidine nucleotides. It attacks at the 3 phosphate end (For example pG-pG-pC-pA-pG will be cleaved to give pG-pG-pCp and A-pG). The highest activity is exhibited with single stranded RNA. RNase A is a single chain polypeptide containing 4 disulfide bridges. In contrast to RNase B it is not a glycoprotein.