3-(Trifluoromethyl)-5678-Tetrahydro-[124]Triazolo[43-A]Pyrazine Hydrochloride 98.0%(HPLC)

Reactant involved in Enantioselective and diastereoselective unpoled carbonyl allylation Syntehsis of organophophine oxides as anittumor agents SN2 halogenation of hydroxy groups Synthesis of BINAP complexes Studies of conformational flexibility of BINAP chelates.

For R&D use onlynot for drug household or other uses.

BINAP (22-bis(diphenylphosphino)-11-binaphthyl) is an organophosphorus compound. This chiral ligand is widely used in asymmetric synthesis. It consists of a pair of 2-diphenylphosphinonaphthyl groups linked at the 1 and 1 positions. This C2-symmetric framework lacks a stereogenic atom but has axial chirality due to restricted rotation (atropisomerism). The barrier to racemization is high due to steric hindrance which limits rotation about the bond linking the naphthyl rings. The dihedral angle is approximately 90.