Synthesis of 4-sulfonyliminopiperidine and its reaction with benzyl Grignard to form an important pharmaceutical building block 4-benzyl-4-aminopiperidne.[1]Also used to prepare spiro tosylaziridines via methylene insertion into the derived sulfonylimine.

For R&D use onlynot for drug household or other uses.

tert-Butanesulfinamide is an organosulfur compound and a member of the class of sulfinamides. Both enantiomeric forms are commercially available and are relevant to the asymmetric synthesis of amines as a chiral ammonia equivalent. This methodology was introduced in 1997 by Jonathan A. Ellman.