Topiramate 98.0%(HPLC)

98.0%(HPLC)


Linear Formula:  C12H21NO8S
Molecular Weight:  339.36g/mol
CAS Number: 97240-79-4

Properties

Vapour pressure 0.0±1.1 mmHg at 25℃
Assay Purity >98%(HPLC)
Refractive index 1.497
B pt. 438.7℃ at 760 mmHg
M pt. 126℃
Density 1.336 g/cm3

Safety Information

Hazard Statement(s) H315-H319
Precautionary Statement  P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364 -P332 + P313
Symbol
Signal word Warning
Flash point 219.1℃
Storage Temp. 0-10℃
Packaging Glass Bottle

Description

Recommended products
Methyl Alpha-D-Glucopyranoside 98.0%(GC)

Application
Topiramate has been used to study the antiaggressive effects of topiramate in mice to study of the effect of topiramate in promoting neurite outgrowth post nerve injury in fetal rat cortical and hippocampal tissues. as a mitochondrial carbonic anhydrase inhibitor to block the effects of high glucose or glucotoxicity. to reduce cell death and mitochondrial dysfunction induced by the administration of kainic acid.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Topiramate has a molar mass of 339 with 40% of this mass being that of oxygen atoms. These oxygen atoms serve as proton acceptors and the amide group functions as a donor for the formation of hydrogen bond. Topiramate is an antiepileptic drug (AED) and is structurally quite distinct from other AEDs as it is derived from D-fructose a naturally occurring sugar moiety and has sulfamate functionality. Topiramate crosses the cell membranes and blood-brain barrier readily.