0.25 M 5-Ethylthiotetrazole Solution (ETT in Anhydrous Acetonitrile) PurOligo

PurOligo


Properties

Vapour pressure 93.6 hPa
Water Solubility Completely soluble
Autoignition temp. No data available
Explosion limit 3-17 vol %
Assay Purity >98%
Refractive index No data available
B pt. 82°C
M pt. -45°C
Density 0.786 g/cm³ at 25°C
Form Liquid

Safety Information

Hazard Statement(s) H225-H302+H312+H332-H319
Precautionary Statement  P210-P280-P303+P361+P353-P304+P340-P312-P305+P351+P338
GHS Pictogram
Signal word Danger
HS Code 292990
Flash point 2°C
Storage Temp. Room Temperature
Storage Class 3 - Flammable liquids
UN Number 1993

Description

Application
0.25 M 5-Ethylthiotetrazole (ETT) Solution in anhydrous acetonitrile is used as an activator reagent in phosphoramidite-based oligonucleotide synthesis for the production of DNA RNA and modified nucleic acid sequences.

Purpose
The purpose of 0.25 M 5-Ethylthiotetrazole Solution is to activate phosphoramidite monomers by promoting efficient coupling reactions during solid-phase oligonucleotide synthesis thereby improving synthesis yield and product quality.

General Description
0.25 M 5-Ethylthiotetrazole Solution (ETT in anhydrous acetonitrile) is a ready-to-use reagent consisting of 5-ethylthiotetrazole dissolved in water-free acetonitrile formulated to provide high reactivity and moisture-sensitive conditions required for automated nucleic acid synthesis.