0.25 M DCI Solution (4, 5-Dicyanoimidazole in Anhydrous Acetonitrile) PurOligo
PurOligo
Properties
| Vapour pressure | 97 hPa |
| Water Solubility | Soluble |
| Explosion limit | Upper explosion limit: 16 %(V) Lower explosion limit: 3 %(V) |
| B pt. | 81°C |
| M pt. | -46°C |
| Form | Liquid |
Safety Information
| Hazard Statement(s) | H225-H302+H312+H332-H315-H318-H335 |
| Precautionary Statement | P210-P280-P303+P361+P353-P304+P340-P312-P305+P351+P338 |
| GHS Pictogram |
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| Signal word | Danger |
| HS Code | 29339990 |
| Flash point | 2°C |
| Storage Temp. | Room Temperature |
| Storage Class | 3 - Flammable liquids |
| UN Number | 1993 |
Description
Other Notes
45-Dicyanoimidazole (DCI) is an efficient activator for use in chemical synthesis of DNA.
Application
It is used as an activator solution during automated solid-phase synthesis of DNA and RNA oligonucleotides.
Purpose
Its main purpose is to activate phosphoramidites so that they can efficiently react with the growing oligonucleotide chain during the coupling step.
General Description
The solution contains 45-dicyanoimidazole (DCI) at a concentration of 0.25 M dissolved in anhydrous acetonitrile. DCI acts as a mild acidic activator and promotes the coupling of nucleoside phosphoramidites with the reactive hydroxyl group on the growing oligonucleotide chain.
Documents
| SDS | |
| COA | |
| Specification | |
| Bulk quote order form | |
| Sample COA |
