1-Carbobenzoxy-2-piperidinecarboxylic Acid PurCert Secondary working Standard [Includes all characterization data]
PurCert
Properties
| B pt. | 443.9±45.0 °C |
| M pt. | 78.0to82.0°C |
| Density | 1.265±0.06 g/cm3 |
| Form | Solid |
Safety Information
| Hazard Statement(s) | H315-H319 |
| Precautionary Statement | P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313Â |
| GHS Pictogram |
|
| Signal word | Warning |
| Storage Temp. | Store at Room Temperature. |
| Storage Class | NA |
Description
Application
It functions as a building block in peptide synthesis and medicinal chemistry for preparing disubstituted azetidinones as cathepsin K inhibitors and PARP inhibitors like ABT-888 for cancer treatment.
Purpose
The Cbz group protects the nitrogen during multi-step organic synthesis allowing selective carboxylic acid activation while introducing piperidine scaffolds into pharmaceuticals to enhance biological activity.
General Description
This compound has the molecular formula CHNO (MW 263.29) appears as a white solid it is the racemic form unless specified as chiral.
Documents
| SDS | |
| COA | |
| Specification | |
| Bulk quote order form | |
| Sample COA |