1-Carbobenzoxy-2-piperidinecarboxylic Acid PurCert Secondary working Standard [Includes all characterization data]
PurCert
Properties
| Assay Purity | >=98% |
| B pt. | 443.9 ± 45.0 °C |
| M pt. | 78.0 to 82.0 °C |
| Density | 1.265 ± 0.06 g/cm3 |
| Form | Solid |
Safety Information
| Hazard Statement(s) | H315-H319 |
| Precautionary Statement | P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338-P362 + P364-P332 + P313Â |
| GHS Pictogram |
|
| Signal word | Warning |
| HS Code | NA |
| Storage Temp. | Store at Room Temperature. |
| Storage Class | NA |
| UN Number | NA |
Description
Application
It functions as a building block in peptide synthesis and medicinal chemistry for preparing disubstituted azetidinones as cathepsin K inhibitors and PARP inhibitors like ABT-888 for cancer treatment.
Purpose
The Cbz group protects the nitrogen during multi-step organic synthesis allowing selective carboxylic acid activation while introducing piperidine scaffolds into pharmaceuticals to enhance biological activity.
General Description
This compound has the molecular formula C14H17NO4(MW 263.29) appears as a white solid it is the racemic form unless specified as chiral.
Documents
| SDS | |
| COA | |
| Specification | |
| Bulk quote order form | |
| Sample COA |
