1-Hydroxybenzotriazole hydrate PurCert Secondary Working Standard [Includes all characterization data]
CRM
Synonym: HOBt Hydrate
Linear Formula:
C6H5N3O · xH2O
Molecular Weight: 135.12 g/mol (anhydrous)
CAS Number: 123333-53-9
Properties
| Water Solubility | Slightly soluble |
| Assay Purity | >=97 % |
| Refractive index | 1.6910 |
| B pt. | 248.8°C |
| M pt. | 155-158 °C |
| Density | 1.065 g/cm3 |
| Form | Solid |
Safety Information
| Hazard Statement(s) | H207,H319,H412 |
| Precautionary Statement | P210 - P212 - P230 - P233 - P280 - P370 + P380 + P375 - P501 |
| GHS Pictogram |
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| Signal word | Danger |
| HS Code | 29339990 |
| Storage Temp. | Room Temperature |
| Storage Class | 4.1A - Other explosive hazardous materials |
| UN Number | 3474 |
Description
Application
It is widely used in peptide synthesis and other coupling reactions to enhance reaction yields and minimize side reactions such as racemization.
Purpose
Its purpose is to activate carboxylic acids and facilitate the formation of stable amide bonds during chemical synthesis.
General Description
1-Hydroxybenzotriazole hydrate (HOBtH2O) is a hydrated organic compound commonly used as a peptide-coupling additive to improve the efficiency of amide bond formation in organic synthesis.
Documents
| SDS | |
| COA | |
| Specification | |
| Bulk quote order form | |
| Sample COA |
