2.0 M Triethylammonium Acetate (TEAA) buffer is commonly used as a buffering and ion-pairing reagent in chromatography especially in reversed-phase HPLC for the separation of nucleotides oligonucleotides and other charged compounds.

Its primary purpose is to maintain a controlled pH and provide triethylammonium ions that interact with negatively charged analytes improving their retention and separation during chromatographic analysis.

2.0 M TEAA buffer is a high-concentration aqueous solution of triethylammonium acetate consisting of triethylammonium ions and acetate ions and commonly used as a volatile-compatible or ion-pairing buffer in analytical chemistry.