3% Dichloroacetic Acid in Dichloromethane PurOligo

PurOligo


Properties

Vapour pressure 470.9 hPa
Water Solubility Completely soluble
Autoignition temp. No data available
Explosion limit Upper explosion limit: 19 %(V), Lower explosion limit: 12 %(V)
Assay Purity NA
Refractive index No data available
B pt. 40°C
M pt. -97°C
Density 1.325 g/cm3 at 25°C
Form Liquid

Safety Information

Hazard Statement(s) H315-H318-H336-H351-H360FD-H400
Precautionary Statement  P202-P273-P280-P302+P352-P305+P351+P338-P308+P313
GHS Pictogram
Signal word Danger
HS Code NA
Flash point No data available
Storage Temp. 5-25°C
Storage Class 6.1D
UN Number 2922

Description

Other Notes

Deblocking solutions used for the cleavage of the 5-DMTr group at the last building block of nucleotide chain can consist either of dichloroacetic or trichloroacetic acid in dichloromethane or toluene.

Application
Peptide synthesis for removal of acid-labile protecting groups. Solid-phase peptide synthesis (SPPS). Organic synthesis and reaction workups. Resin deprotection and cleavage procedures. Laboratory research and analytical chemistry.

Purpose
Laboratory use

General Description
3% Dichloroacetic Acid (DCA) in Dichloromethane (DCM) is a reagent solution containing 3% dichloroacetic acid dissolved in dichloromethane. It is commonly used in organic synthesis and peptide chemistry as a mild acidic deprotection reagent.