6-Aminopenicillanic acid PurCert Secondary Reference Standard (CRM) [Includes all characterization data]

PurCert


Properties

Vapour pressure 0.0000038 hPa at 25 °C
Water Solubility 2.46 g/l at 20 °C
Autoignition temp. > 400 °C at 1013 hPa
Assay Purity >= 99.5 %
Refractive index n20/D 1.630
B pt. 426 °C
M pt. 198-200 °C
Density 1.341 g/cm3
Form Solid

Safety Information

Hazard Statement(s) H319
Precautionary Statement  P264 - P280 - P305 + P351 + P338 - P337 + P313
GHS Pictogram
Signal word Warning
HS Code 29349990
Storage Temp. 2-8°C
Storage Class 11 - Combustible Solids

Description

Application
6-Aminopenicillanic acid (6-APA) is primarily used as the core building block in the pharmaceutical production of semisynthetic penicillin antibiotics such as Amoxicillin and Ampicillin.

Purpose
Its purpose is to provide a chemically modifiable nucleus that allows scientists to create a wide variety of penicillin derivatives with improved antibacterial activity stability and resistance to enzymes like those involved in antibiotic resistance.

General Description
6-Aminopenicillanic acid is a chemical compound consisting of a beta-lactam ring fused to a thiazolidine ring forming the essential structural backbone responsible for the antibacterial properties of penicillin-class drugs.