Capping B (THF / N-methylimidazole / Pyridine, V / V / V = 80 : 10 : 10) PurOligo


Properties

Water Solubility Soluble
Explosion limit Upper explosion limit: 12.4 %(V) Lower explosion limit: 1.5 %(V)
Refractive index 1.427-1.430
B pt. 64°C
Form Liquid

Safety Information

Hazard Statement(s) H225-H302+H312-H314-H335-H336-H351-EUH019
Precautionary Statement  P210-P280-P303+P361+P353-P304+P340-P310-P305+P351+P338
GHS Pictogram
Signal word Danger
HS Code 38229090
Flash point -20°C
Storage Temp. 5-20 °C
Storage Class 3 - Flammable liquids
UN Number 2924

Description

Purpose
To promote the acetylation (capping) of unreacted 5-hydroxyl groups preventing their participation in subsequent coupling cycles and thereby minimizing deletion sequences.

General Description
A liquid reagent blend of tetrahydrofuran (THF) N-methylimidazole and pyridine used as the catalyst solution in the capping step of automated oligonucleotide synthesis.