It is applied as an osmotic diuretic in medicine excipient in pharmaceuticals (tablets syrups) low-calorie sweetener in food and stabilizer in cosmetics.

Its primary purpose is to reduce intracranial or intraocular pressure via osmosis provide bulk and sweetness without full caloric absorption and act as a cryoprotectant or diagnostic agent in renal function tests.

D-Mannitol (C6H14O6) is a white odorless crystalline sugar alcohol with a sweet taste featuring a straight-chain hexitol structure derived from mannose with six hydroxyl groups and a melting point around 165 170 C