Dorzolamide Hydrochloride PurCert Secondary Reference Standard (CRM) [Includes all characterization data]
PurCert
Synonym: Dorzolamide hydrochloride
Linear Formula:
C10H16N2O4S3.HCl
Molecular Weight: 360.90 g/mol
CAS Number: 130693-82-2
Properties
| Water Solubility | Soluble |
| Assay Purity | >=98% |
| M pt. | 283 - 285°C |
| Density | 1.530 g/cm3 |
| Form | Solid |
Safety Information
| Hazard Statement(s) | H302,H373 |
| Precautionary Statement | P260 - P264 - P270 - P301 + P312 - P314 - P501 |
| GHS Pictogram |
|
| Signal word | Warning |
| HS Code | 29359040 |
| Storage Temp. | Room Temperature |
| Storage Class | 11 - Combustible Solids |
| UN Number | NA |
Description
Application
It is applied as eye drops (typically 2% solution) directly into the affected eye(s) usually 2-3 times daily either as monotherapy or adjunctive therapy with beta-blockers.
Purpose
Dorzolamide Hydrochloride treats elevated intraocular pressure in open-angle glaucoma ocular hypertension and pseudo-exfoliative glaucoma by inhibiting carbonic anhydrase II to reduce aqueous humor production.
General Description
Dorzolamide Hydrochloride is the hydrochloride salt form of dorzolamide a carbonic anhydrase inhibitor described chemically as (4S-trans)-4-(ethylamino)-56-dihydro-6-methyl-4H-thieno[23-b]thiopyran-2-sulfonamide 77-dioxide monohydrochloride formulated as a topical ophthalmic solution
Documents
| SDS | |
| COA | |
| Specification | |
| Bulk quote order form | |
| Sample COA |
