Fmoc-L-Cit-OH is commonly used in solid-phase peptide synthesis (SPPS) for the production of synthetic peptides peptide-based drug candidates and biochemical research materials containing L-citrulline residues.

The primary purpose of Fmoc-L-Cit-OH is to provide a protected L-citrulline building block that can be selectively incorporated into peptides during stepwise synthesis without unwanted side reactions at the amino group.

Fmoc-L-Cit-OH is a protected form of the amino acid L-citrulline in which the amino group is blocked by the fluorenylmethoxycarbonyl (Fmoc) protecting group making it suitable for peptide synthesis.