N-Ethylmaleimide, PurReagent, >=98.0%
PurReagent
Synonym: N-Ethylmaleimide, NEM
Linear Formula:
C6H7NO2
Molecular Weight: 125.13 g/mol
CAS Number: 128-53-0
Properties
| Water Solubility | Slightly Soluble |
| Assay Purity | >=98% |
| B pt. | 210 °C |
| M pt. | 43 - 46 °C |
| Form | Solid |
Safety Information
| Hazard Statement(s) | H300,H311,H314,H317 |
| Precautionary Statement | P260 - P272 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| GHS Pictogram |
|
| Signal word | Danger |
| HS Code | NA |
| Flash point | 72.9 °C |
| Storage Temp. | Room Temperature |
| Storage Class | 6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials |
| UN Number | 2928 |
Description
Application
Blocking free thiol groups in proteins and enzymes. Preventing oxidation of cysteine residues during sample preparation. Studying protein structure function and enzyme mechanisms. Inhibiting thiol-dependent enzymes. Preserving cellular redox states in biochemical experiments.
Purpose
The primary purpose of NEM is to irreversibly modify and protect sulfhydryl groups allowing researchers to control thiol-related reactions and investigate protein function and cellular processes.
General Description
N-Ethylmaleimide (NEM) is a thiol-reactive organic compound commonly used in biochemistry and molecular biology. It selectively reacts with sulfhydryl (-SH) groups present in cysteine residues of proteins.
Documents
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| COA | |
| Specification | |
| Bulk quote order form |