N-Methyl-L-alanine PurCert Analytical Standard

PurCert


Properties

Assay Purity >= 95 %
B pt. 190.1±23.0 °C
M pt. 315-317°C
Density 1.048±0.06 g/cm3
Form Solid

Safety Information

GHS Pictogram
HS Code 2922498590
Storage Temp. Room temperature
Storage Class 11 - Combustible Solids

Description

Application
It serves as a building block in peptide synthesis particularly for solution-phase peptides and site-specific antibody-drug conjugates like trastuzumab maytansinoids and as a research reagent in biochemical studies.

Purpose
N-Methyl-L-alanine introduces steric and conformational effects in peptides enhancing stability against proteases and modifying receptor interactions in pharmacological research.

General Description
N-Methyl-L-alanine is a non-proteinogenic amino acid derivative with the molecular formula CHNO CAS number 3913-67-5 and molecular weight of 103.12 gmol featuring an N-methyl group on the L-alanine structure appearing as a white to off-white solid that decomposes at 315-317C with limited solubility in water and aqueous acids.