Propafenone Hydrochloride PurCert Secondary Reference Standard (CRM) [Includes all characterization data]

PurCert


Properties

Assay Purity >= 99 %
M pt. 165-1670°C
Form Solid

Safety Information

Hazard Statement(s) H302
Precautionary Statement  P264 - P270 - P301 + P312 - P501
GHS Pictogram
Signal word Warning
HS Code 2922504500
Storage Temp. Room Temperature
Storage Class 11 - Combustible Solids

Description

Application
It is primarily used as an oral antiarrhythmic medication in tablet or capsule form for treating life-threatening ventricular arrhythmias and supraventricular tachycardias. It functions as a sodium channel blocker with weak beta-blocking and calcium channel blocking effects.

Purpose
Its main purpose is to stabilize cardiac cell membranes slow conduction in the His-Purkinje system and prolong PR and QRS intervals to control abnormal heart rhythms like paroxysmal supraventricular tachycardia and ventricular arrhythmias.

General Description
Propafenone Hydrochloride is a white to white crystalline powder the hydrochloride salt of propafenone with a molecular weight of 377.9 gmol. it is slightly soluble in water soluble in methanol and exhibits maximum absorption at 303 nm. This action slows the electrical signals that cause the heart to beat helping to stabilize the hearts rhythm. It is typically available as tablets or extended-release capsules and appears as a white crystalline powder in its raw form.