R 406 (Tamatinib) (free base) PurReagent 98.0%

R 406 (Tamatinib) (free base), PurReagent, >=98.0%

PurReagent

Synonym: 6-[[5-Fluoro-2-[(3,4,5-trimethoxyphenyl)amino]-4-pyrimidinyl]amino]-2,2-dimethyl-2H-pyrido[3,2-b]-1,4-oxazin-3(4H)-one, N4-(2,2-dimethyl-3-oxo-4H-pyrid[1,4]oxazin-6-yl)-5-fluoro-N2-(3,4,5-trimethoxyphenyl)-2,4-pyrimidinediamine, R 406 (free base), Tamatin

Linear Formula: C₂₂H₂₃FN₆O₅

Molecular Weight: 470.45 g/mol

CAS Number: 841290-80-0

Properties

Water Solubility	at 20 °C practically insoluble
Assay Purity	>=98%
M pt.	182-184°C
Density	1.358 ± 0.06 g/cm3
Form	Solid

Safety Information

GHS Pictogram
HS Code	29349990
Storage Temp.	-20°C
Storage Class	11 - Combustible Solids

Description

Application

R406 is applied in the treatment and study of immune-related diseases inflammatory disorders and certain blood platelet conditions.

Purpose

The main purpose of R406 is to block SYK enzyme activity thereby reducing abnormal immune responses and inflammation in the body.

General Description

R406 is an orally active pharmacological compound and the active metabolite of Fostamatinib known for its role in inhibiting immune cell signaling pathways

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