Romidepsin PurCert Standard
PurCert
Properties
| Assay Purity | >=98% |
| B pt. | 942.8±65.0 °C |
| M pt. | 219 - 224°C |
| Density | 1.174 |
| Form | Solid |
Safety Information
| Hazard Statement(s) | H302-H315-H319-H335 |
| Precautionary Statement | P261-P305+P351+P338 |
| GHS Pictogram |
|
| Signal word | Warning |
| HS Code | 29349990 |
| Storage Temp. | Room Temperature |
| Storage Class | 11 - Combustible Solids |
| UN Number | NA |
Description
Application
It is FDA-approved as Istodax for treating cutaneous and peripheral T-cell lymphomas in relapsed or refractory patients administered intravenously.
Purpose
Functions as a histone deacetylase (HDAC) inhibitor to induce cancer cell apoptosis cell cycle arrest and epigenetic modulation by hyperacetylating histones and non-histone proteins.
General Description
Romidepsin is a bicyclic depsipeptide HDAC inhibitor derived from Chromobacterium violaceum featuring formula CHNOS (MW 540.7 gmol) with a reducible disulfide bond that activates its binding to class I HDAC enzymes.
Documents
| SDS | |
| COA | |
| Specification | |
| Bulk quote order form | |
| Sample COA |
