Unylinker-OH Resin is used as a universal solid support for the automated solid-phase synthesis of DNA RNA and modified oligonucleotides allowing the preparation of sequences with a free 3-hydroxyl terminus.

Its purpose is to provide a stable and universal linker between the growing oligonucleotide chain and the solid support enabling efficient synthesis and subsequent cleavage of the completed oligonucleotide under standard deprotection conditions.

Unylinker-OH Resin is a functionalized solid-phase synthesis resin containing a universal hydroxyl linker that is compatible with phosphoramidite chemistry making it suitable for the synthesis of a wide variety of DNA RNA and chemically modified oligonucleotides without requiring a base-specific support.