1-Bromo-4-Fluoronaphthalene 97.0%(GC)

Celastrol has been used intraperitoneally to inject into experimental mice to study its role in nonalcoholic fatty liver disease (NAFLD) used in culture medium to study its effect on lipopolysaccharide-induced inflammatory injury in human keratinocyte cell culture used to study its effect in vitro and in vivo in VCaP cells.

For R&D use onlynot for drug household or other uses.

Celastrol (tripterine) is a chemical compound isolated from the root extracts of Tripterygium wilfordii (Thunder god vine) and Celastrus regelii. Celastrol is a pentacyclic triterpenoid and belongs to the family of quinone methides. In in vitro and in vivo animal experiments celastrol exhibits antioxidant anti-inflammatory anticancer and insecticidal activities. It has been shown to have obesity-controlling effects in mice. Celastrol has also shown to possess (by inhibition of NF-B in the hypothalamus) anti-diabetic effects on diabetic nephropathy and improve whole-body insulin resistance.