3-Hydroxynaphthalene-2-carboxylic Acid (34-Dihydroxybenzylidene)hydrazide

Dynasore hydrate has been used for priming fetal mesenchymal stemstromal cells (fMSC) in confocal microscopy in wound healingscratch and tube-formation assay to analyse its effects on Coxsackievirus A9 (CAV9) infection to inhibit clathrin-mediated endocytosis and caveolin-mediated endocytosis in live imaging of cells

For R&D use onlynot for drug household or other uses.

Dynasore is a small molecule GTPase inhibitor that targets dynamin-1 dynamin-2 and Drp1 (mitochondrial). Dynasore blocks dynamin-dependent endocytosis scission of endocytic vesicles. Dynosore is profibrotic induces PAI-1 in pleural mesothelial cells and may be an effective pleurodesing (pleurodesis) agent. Dynasor blocks human papillomavirus type 16 (HPV16) and bovine papillomavirus type 1 (BPV1) (pseudovirions) infections. Dynasore hydrate lowers labile cholesterol in the plasma membrane and distorts lipid raft organization.Dynasore exhibits pleotropic effects on herpes simplex virus (HSV)-1 and HSV-2 infection. It hinders viral entry trafficking of viral proteins and capsid formation.