Retinoic Acid 93.0%(HPLC)

93.0%(HPLC)


Synonym:  Vitamin A Acid
Linear Formula:  C20H28O2
Molecular Weight:  300.435 g/mol
CAS Number: 302-79-4

Properties

Vapour pressure 0.0±2.5 mmHg at 25℃
Water Solubility Insoluble
Assay Purity >93%(HPLC)
Refractive index 1.556
B pt. 462.8℃ at 760 mmHg
M pt. 180℃
Density 1.011 g/cm3

Safety Information

Hazard Statement(s) H302 - H315
Precautionary Statement  P264 - P270 - P280 - P301 + P312 - P302 + P352 - P332 + P313
Symbol
Signal word Warning
HS Code 2916209090
Flash point 350.6℃
Storage Temp. Store under inert gas
Storage Class 9
Packaging Glass bottle
UN Number 3077

Description

Recommended products
Vitamin A Acid

Application
Retinoic acid (RA) has been used for the differentiation of embryonic stem cells into motor neurons. It has been used for the differentiation of Xenopus ectoderm into pancreas. It has also been used to study epigenetic regulation by RAR (retinoic acid receptor ) It has been used to study RA signaling of prospermatogonia transition into spermatogonia.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Retinoic acid is a metabolite of vitamin A (retinol) that mediates the functions of vitamin A required for growth and development. Retinoic acid is required in chordate animals which includes all higher animals from fish to humans. During early embryonic development retinoic acid generated in a specific region of the embryo helps determine position along the embryonic anteriorposterior axis by serving as an intercellular signaling molecule that guides development of the posterior portion of the embryo. It acts through Hox genes which ultimately control anteriorposterior patterning in early developmental stages.