1-Cinnamyl-4-diphenylmethylpiperazine

Cinnarizine has been used to block pressure-dependent changes in potassium currents in acutely isolated inner hair cells of the guinea-pig cochlea using whole-cell voltage-clamp techniquesIt has also been used in thein vivoandin vitrostudies to analyze the impact of drug load and physical form of cinnarizine in self-nanoemulsifying drug delivery systems (SNEDDS) on absorption in rats.Cinnarizine has been used to study its role in self-nano emulsifying drug delivery systems (SNEDDS) to test Ca2 signaling is pivotal for cancer-associated fibroblasts (CAFs) retraction

For R&D use onlynot for drug household or other uses.

Cinnarizine is a piperazine derivativewhich is extracted from wood reed roots.It exhibits antihistaminic and calcium antagonist property. Cinnarizine is used to treat vertigounsteadiness and cognitive disorders.Cinnarizine has anticholinergic antiserotonergic and antidopaminergic effects. It enhances cerebral blood flow. Cinnarizine blocks the contraction of smooth muscles cells and also acts as a skin whitening agent.