Gamma-Crotonolactone 93.0%(GC)

93.0%(GC)


Synonym:  2(5H)-Furanone
Linear Formula:  C4H4O2
Molecular Weight:  84.07g/mol
CAS Number: 497-23-4

Properties

Vapour pressure 0.273mmHg at 25℃
Assay Purity >93%(GC)
Refractive index n20/D 1.469 (lit.)
B pt. 86-87 ℃/12 mmHg (lit.)
M pt. 4-5 ℃(lit.)
Density 1.185 g/mL at 25 ℃ (lit.)

Safety Information

Hazard Statement(s) H315-H319
Precautionary Statement  P264-P280-P302 + P352-P337 + P313-P305 + P351 + P338 -P362 + P364-P332 + P313
Symbol
Signal word Warning
HS Code 29322980
Flash point 101℃
Storage Temp. 2-8℃
Storage Class 6.1
Packaging Glass Bottle
UN Number 1711

Description

Application
2(5H)-Furanone (-Crotonolactone) has been used in synthesis of ()-L-733060 ()-CP-99994 and (2S3R)-3-hydroxypipecolic acid synthesis of 5-substituted 2(5H) furanones (-butenolides) via direct aldol reaction with aromatic aldehydes catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts Michael addition reactions[5] for synthesis of lignans.

Purpose
For R&D use onlynot for drug household or other uses.

General Description
Chiral urea compounds catalyzed hetero-Michael addition reaction of 2(5H)-furanone (-crotonolactone) to pyrrolidine[1]. The quorum sensing inhibition activity by 2(5H)-furanone was studied using bioindicator strains